F. M. Kirby Research Center for Functional Brain Imaging
At the Kennedy Krieger Institute

Guanshu Liu, PhD

Affiliated Faculty
F.M. Kirby Research Center for Functional Brain Imaging
Assistant Professor
Department of Radiology, Johns Hopkins University School of Medicine

Guanshu Liu, PhD

Biographical Sketch

Guanshu Liu, Ph.D., is currently a tenure track Assistant Professor in the F.M. Kirby Center at the Kennedy Krieger Institute and the Russell H. Morgan Department of Radiology and Radiological Science at Johns Hopkins Medical School. Dr. Guanshu Liu earned his doctoral degree in biomedical engineering at Case Western Reserve University. Then he joined Dr. Peter van Zijl's imaging center at Johns Hopkins University in 2008 as a Research Associate.

Research Summary

The primary goal of my research is to develop novel Magnetic Resonance (MR) molecular imaging techniques to facilitate the development of modern medicine. As a relatively young but revolutionary discipline, MR molecular imaging aims at expanding traditional MRI from a macroscopic anatomical scale to a cellular and subcellular scale on which specific molecular markers can be specifically visualized, characterized and quantified in correspondence to a disease stage or a treatment response. As such, MR molecular imaging plays a key role in translating those discoveries in basic biomedical researches to clinical practices. My current researches mainly focus on the development and applications of a novel MRI technique, so called Chemical Exchange Saturation Transfer (CEST). We are currently developing a variety of nanoparticle-based CEST imaging probes with low toxicity, high sensitivity and high specificity, and exploring the biomedical applications of these new imaging probes. In addition, we are also interested in exploring the biomedical uses of endogenous CEST contrast. For example, one of ongoing projects in my lab focuses on exploiting the endogenous CEST MRI signal of bacterial organisms for detecting and monitoring bacterial infection in rodent models.

Contact Information

Office Address
F.M. Kirby Center, Kennedy Krieger Institute
Department of Radiology, Johns Hopkins University
707 N. Broadway, Baltimore MD 21205

Email Address
guanshu@mri.jhu.edu

Phone Number
(443) 923-9500

Curriculum Vitae

  • Current Appointments
    • Affiliated Faculty, F. M. Kirby Research Center for Functional Brain Imaging
      12/2012 - Present
      Instructor: 2010-2012
      Research Associate: 2008 - 2009
      Kennedy Krieger Institute, Baltimore, MD
    • Assistant Professor, Department of Radiology and Radiological Science
      12/2012 - Present
      Instructor: 2010-2012
      Research Associate: 2008 - 2009
      Johns Hopkins University, Baltimore, MD
  • Education and Training
    • Ph.D., Biomedical Engineering, Case Western Reserve University, 2004-2008
    • M.S., Analytical Chemistry, University of Missouri-Rolla, 2001-2003
    • M.S., Photochemistry and Photobiology, Chinese Academy of Sciences, 1998-2001
    • B.S., Applied Chemistry, University of Science and Technology of China, 1993-1998

Publications

For a list of Guanshu Liu's most recent publications searched from the NIH's PubMed Database, please use this Search Link or to the frame below.